Risks of Anti-Inflammatory Drug usage (NSAIDs commonly known as pain killers) in long term and even short term are very high regarding their association with kidney injury, increase in blood pressure, Heart failure exacerbation (in patients with history of Heart disease) and peptic ulcer disease. In USA & Pakistan they are used heavily and self-prescribed for pain and commonly known as magic drug (Dard ki dawa) for every pain. It is hitting home for many of us as our beloved ones may end up in the Emergency room with a hypertensive crisis (blood pressure above 180 systolic / 110 diastolic) at a range where it starts affecting our vital organs. The reason behind this, most of the time is due to usage of NSAIDs such as (Meloxicam, Piroxicam, Nimesulide) for toothache, Backache, joint pain etc. prescribed by the pharmacists/dentist and most of the time self-prescribed. As in Pakistan they are sold over the counter without having any prescription and without any monitoring.
As a Nephrologist (Kidney Disease Specialist), we end up seeing way too often people on those medications with no monitoring that end up in renal failure or congestive heart failure exacerbation. I would like to raise this awareness to the public with the goal of having them avoid this type of drug if they have the above diagnosis and to have their blood pressures and kidney function checked if they are using it.